American Board of Internal Medicine, Endocrinology, Diabetes and Metabolism Subspecialty
UCSF Department of Medicine
UCSF Bariatric Surgery Program
Dr. Schafer is Assistant Professor of Medicine and of Epidemiology & Biostatistics at UCSF and a practicing endocrinologist at the San Francisco VA Medical Center. She is board-certified in by the American Board of Internal Medicine in Internal Medicine and by the American Board of Internal Medicine in Endocrinology, Diabetes and Metabolism Subspecialty.
Her research focus is on osteoporosis and metabolic bone disease. One of her specific research emphases is osteoporosis treatment and the assessment of response to osteoporosis therapy. Pharmacologic treatment for osteoporosis may involve the use of an antiresorptive agent (one that decreases bone resorption) or an anabolic agent (one that stimulates bone formation). Dr. Schafer and colleagues conducted a randomized, placebo-controlled trial testing two innovative combinations of concurrent and sequential anabolic and anti-resorptive therapy in postmenopausal women with low bone mass. Findings from the trial may help to expand treatment options for osteoporosis. Additionally, Dr. Schafer is actively engaged in research involving the relationship between bone and fat. Bone-fat interplay—including the effects of fat on bone metabolism and the skeletal regulation of energy metabolism—is an area of increasing investigation. Currently, she is studying the effects of bariatric surgery (surgical weight loss) on calcium metabolism and skeletal health. Her research is funded by the U.S. Department of Veterans Affairs, the National Institutes of Health (National Institute on Diabetes and Digestive and Kidney Diseases), and the American Society for Bone and Mineral Research.
Schafer AL. Vitamin D and Intestinal Calcium Transport After Bariatric Surgery. J Steroid Biochem Mol Biol. 2016 Dec 24. View in PubMed
Kim TY, Schafer AL. Diabetes and Bone Marrow Adiposity. Curr Osteoporos Rep. 2016 Dec; 14(6):337-344. View in PubMed
Napoli N, Schafer AL, Lui LY, Cauley JA, Strotmeyer ES, Le Blanc ES, Hoffman AR, Lee CG, Black DM, Schwartz AV. Serum 25-hydroxyvitamin D level and incident type 2 diabetes in older men, the Osteoporotic Fractures in Men (MrOS) study. Bone. 2016 Sep; 90:181-4. View in PubMed
Kim TY, Schafer AL. Variability in DXA Reporting and Other Challenges in Osteoporosis Evaluation. JAMA Intern Med. 2016 Mar 1; 176(3):393-5. View in PubMed
Schafer AL. Decline in Bone Mass During Weight Loss: A Cause for Concern? J Bone Miner Res. 2016 Jan; 31(1):36-9. View in PubMed
Katzman WB, Vittinghoff E, Kado DM, Schafer AL, Wong SS, Gladin A, Lane NE. Study of Hyperkyphosis, Exercise and Function (SHEAF) Protocol of a Randomized Controlled Trial of Multimodal Spine-Strengthening Exercise in Older Adults With Hyperkyphosis. Phys Ther. 2016 Mar; 96(3):371-81. View in PubMed
Schafer AL, Weaver CM, Black DM, Wheeler AL, Chang H, Szefc GV, Stewart L, Rogers SJ, Carter JT, Posselt AM, Shoback DM, Sellmeyer DE. Intestinal Calcium Absorption Decreases Dramatically After Gastric Bypass Surgery Despite Optimization of Vitamin D Status. J Bone Miner Res. 2015 Aug; 30(8):1377-85. View in PubMed
Schafer AL, Li X, Schwartz AV, Tufts LS, Wheeler AL, Grunfeld C, Stewart L, Rogers SJ, Carter JT, Posselt AM, Black DM, Shoback DM. Changes in vertebral bone marrow fat and bone mass after gastric bypass surgery: A pilot study. Bone. 2015 May; 74:140-5. View in PubMed
Wheeler AL, Tien PC, Grunfeld C, Schafer AL. Teriparatide treatment of osteoporosis in an HIV-infected man: a case report and literature review. AIDS. 2015 Jan 14; 29(2):245-6. View in PubMed
Win AZ, Ceresa C, Schafer AL, Mak P, Stewart L. Importance of nutrition visits after gastric bypass surgery for American veterans, San Francisco, 2004-2010. Prev Chronic Dis. 2014; 11:E226. View in PubMed
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